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rabbit polyclonal anti ho1  (Bioss)


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    Bioss rabbit polyclonal anti ho1
    Rabbit Polyclonal Anti Ho1, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit polyclonal anti ho1/product/Bioss
    Average 94 stars, based on 15 article reviews
    rabbit polyclonal anti ho1 - by Bioz Stars, 2026-06
    94/100 stars

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    A schematic illustration of potential CFTR-Nrf2-HO1/NQO1 pathways that might mitigate gentamicin-induced hearing loss. Gentamicin causes accumulation of ROS in cochlear hair cells, resulting in oxidative stress imbalance and ultimately hair cell death. Ivacaftor plays an antioxidant role by activating the CFTR-Nrf2-HO1/NQO1 axis to protect sensory hair cells.

    Journal: Redox Report : Communications in Free Radical Research

    Article Title: Ivacaftor attenuates gentamicin-induced ototoxicity through the CFTR-Nrf2-HO1/NQO1 pathway

    doi: 10.1080/13510002.2024.2332038

    Figure Lengend Snippet: A schematic illustration of potential CFTR-Nrf2-HO1/NQO1 pathways that might mitigate gentamicin-induced hearing loss. Gentamicin causes accumulation of ROS in cochlear hair cells, resulting in oxidative stress imbalance and ultimately hair cell death. Ivacaftor plays an antioxidant role by activating the CFTR-Nrf2-HO1/NQO1 axis to protect sensory hair cells.

    Article Snippet: The primary antibodies used for western blot were as follows: mouse monoclonal anti-CFTR (66928-1-Ig, Proteintech, CN), Rabbit polyclonal anti-Nrf2 (16396-1-AP, Proteintech, CN), rabbit polyclonal anti-HO1 (ab52947, Abcam, USA), NQO1 (ab80588, Abcam, USA), SOD2 (66474-1-Ig, Proteintech, CN), and Keap1 (10503-2-AP, Proteintech, CN), anti-Cleaved Caspase 3 (25128-1-AP, Proteintech, CN), anti-beta actin (66009-1-Ig, Proteintech, CN), anti-Laminb1 (66095-1-Ig, Proteintech, CN), anti-GAPDH (10494-1-AP, Proteintech, CN).

    Techniques: